Wednesday, November 6, 2013
7:00 a.m.

Registration and Continental Breakfast

8:00 a.m.
Welcome & Opening Remarks
Raju Kucherlapati, Ph.D.
Paul C. Cabot Professor of Genetics, Professor of Medicine, Harvard Medical School
 
Joseph B. Martin, M.D., Ph.D.
Edward R. and Anne G. Lefler Distinguished Professor of Neurobiology, Harvard Medical School
 
Scott Weiss, M.D., M.S.
Scientific Director, Partners HealthCare Center for Personalized Genetic Medicine; Associate Director, Channing Laboratory; Professor of Medicine, Harvard Medical School

 

Margaret Foti, Ph.D., M.D. (h.c.)
Chief Executive Officer
American Association for Cancer Research
8:30 a.m.
Keynote

 

"Personalized Medicine; For Changing Tomorrow"

 
 
 
Yoshihiko Hatanaka
President and CEO
Astellas Pharma, Inc.
 
Introducer:
Stephen Eck, M.D., Ph.D.
Vice President, Global Head of Medical Oncology, Astellas Pharma Global Development Inc.
9:00 a.m.
Panel
 
"The Future is Now: Genomic Sequencing at Work in the Clinic"
 
Human genome sequencing promises to be an important tool in assessing risk, diagnosing disease and stratifying patient populations for targeted therapy. This panel will discuss how this rapidly advancing technology is impacting clinical practice today including some of the personal experiences.
Moderator:
Bruce Johnson, M.D.
Chief Clinical Research Officer, Dana Farber Cancer Institute; Professor of Medicine, Harvard Medical School 
 
Lukas Wartman, M.D.
Instructor of Medicine, Washington University Medical School 
 
Timothy Harkins, Ph.D.
Director of Research & Development, Advanced Applications Development 
Life Technologies
 
Arthur Beaudet, M.D.
Henry and Emma Meyer Professor and
Chair, Molecular and Human Genetics
Baylor College of Medicine
 
Heidi Rehm, Ph.D., FACMG
Director, Laboratory for Molecular Medicine, Partners HealthCare Center for Personalized Genetic Medicine; Associate Professor of Pathology, Harvard Medical School
10:00 a.m.
Networking Break
 
10:30 a.m.

Panel

"How Leading Professional Societies are Adopting Personalized Medicine"
 
Many medical societies are engaging their members in discussions about the current and future role of personalized medicine in healthcare, and the importance of understanding and advancing the field. During this panel, current and future presidents of leading professional societies discuss how their organizations are educating their members on personalized medicine and supporting its adoption into routine medical practice. 
 
 
 
Moderator:
Anna Barker, Ph.D.
Director, Transformative Healthcare Knowledge Networks; Co-Director, Complex Adaptive Systems Initiative; Professor, School of Life Sciences
Arizona State University
 
ACMG: Gail Herman, M.D., Ph.D., FACMG
Investigator, Center for Molecular and Human Genetics, The Research Institute at Nationwide Children’s Hospital; Professor, Department of Pediatrics, The Ohio State University College of Medicine
 
 
ASCO: Clifford Hudis, M.D., FACP
Chief, Breast Cancer Medical Service & Attending Physician, Memorial Sloan-Kettering Cancer Center; Professor, Department of Medicine, Weill Cornell Medical College
 
ASHG: Cynthia Morton, Ph.D.
William Lambert Richardson Professor of Ob/Gyn and Professor of Pathology, Brigham and Women’s Hospital
 
AACR: Charles Sawyers, M.D.
Investigator, Howard Hughes Medical Institute; Chairman, Human Oncology & Pathogenesis Program, Memorial Sloan-Kettering Cancer Center
 
11:30 a.m.
Presentation of Personalized Medicine Coalition's
Ninth Annual Award for Leadership in
Personalized Medicine
Award Recipient:
Kathy Giusti
Founder & CEO, Multiple Myeloma Research Foundation
 
Introducer:
Edward Abrahams, Ph.D.
President, Personalized Medicine Coalition
 
Presenter:
William S. Dalton, M.D., Ph.D.
Director, Personalized Medicine Institute, Moffit Cancer Center; CEO, M2Gen
12:00 p.m.  - 1:00 p.m.
Luncheon
 Open Seating
 1:15 p.m.
Keynote
 
 "Accelerating Medical Solutions"
Michael Milken, M.B.A.
Chairman, The Milken Institute
Founder, FasterCures
 
Introducer:
Richard Hamermesh, D.B.A.
MBA Class of 1961 Professor of Management Practice; Faculty Chair, HBS Healthcare Initiative, Harvard Business School
 
 2:00 p.m. Keynote
 
Review from the leader of the Food and Drug Administration’s (FDA) program in drug development and companion diagnostics of how the FDA promotes personalized medicine.
Elizabeth Mansfield, Ph.D.
Director of the Personalized Medicine Program in the Office of In Vitro Diagnostics and Radiological Health, FDA
 
Introducer:
Gregory Downing, D.O., Ph.D.
Executive Director for Innovation,
U.S. Department of Health and Human Services
 2:30 p.m.
Networking Break
 
 3:00 p.m.

 Keynote

"Stand up to Cancer"

 
Margaret Foti, Ph.D., M.D. (h.c.)
Chief Executive Officer
American Association for Cancer Research
 3:30 p.m.

 Keynote

"PhRMA's Outlook on Personalized Medicine"

William Chin, M.D.
Executive Vice President of Science and Regulaatory Affairs, PhRMA
 
Introducer:
Richard Maas, M.D., Ph.D.
Professor of Medicine, Harvard Medical School Division of Genetics, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School
4:00 p.m.

Panel

"The Challenges and Opportunities for Commercializing Personalized Medicine"
 
While personalized medicine offers great promise to patients, the business case for developing and commercializing targeted therapies and other tools and technologies is sometimes unclear. In an environment of constrained spending, how can these innovations evolve into successful business models? This panel will explore proven business models, as well as emerging trends and opportunities for new businesses.
Moderator:
Deborah Dunsire, M.D.
CEO and President
EnVivo Pharmaceuticals
 
Chris Garabedian
President & CEO,
Sarepta Therapeutics
 
Barbara McAneny, M.D.
CEO and Medical Director, Innovative Oncology Business Solutions, New Mexico Cancer Center;
President-elect, AMA
 
Matthew Zubiller
Vice President, Decision Management,
McKesson
 5:00 p.m.
Reception at Elements Café
 
 Thursday, November 7, 2013
 7:30 a.m.
Registration & Continental Breakfast
 8:30 a.m.
Keynote
 
"CMS Beneficiaries and the Role of Personalized Medicine in Improving American Healthcare"
 
Shari Ling, M.D.
Deptuy Chief Medical Officer, Centers for Medicare and Medicaid Services
 
Introducer:
Edward Abrahams, Ph.D.
President, Personalized Medicine Coalition
 
 9:00 a.m.
Harvard Business School Discussion
 
"Role of Not-for-Profit Organizations in
Healthcare Innovation"
 
Not-for-Profit organizations are playing increasingly important roles in bringing together patients and drug development organizations to rapidly develop novel and effective drugs. This panel will discuss several success stories.
Leader:
Richard Hamermesh, D.B.A.
MBA Class of 1961 Professor of Management Practice; Faculty Chair, HBS Healthcare Initiative
Harvard Business School
 
Discussants:
Margaret Anderson
Executive Director, FasterCures/The Center for Accelerating Medical Solutions
 
Kathy Giusti
Founder & CEO, Multiple Myeloma Research Foundation
 
Joe O'Donnell
Chairman of Centerplate 
10:15 a.m.
Networking Break
10:45 a.m.
Panel
 
"Building an Evidence Base to Support Molecular Diagnostic Reimbursement"
 
Developing molecular diagnostics is a complex process. So is deciding how to reimburse the use of such diagnostics. This panel will explore current reimbursement models and what is required for value based reimbursement.
Moderator:
Jeanne De Sa
Sr. Vice President, Public Policy and Strategy, United Health Center for Health Reform and Modernization, UnitedHealth Group 
 
Kathryn Phillips, Ph.D.
Professor of Health Economics and Health Services Research; Director, UCSF Center for Translational and Policy Research on Personalized Medicine, University of California, San Francisco

 

Joanne Armstrong, M.D., M.P.H.
Senior Director, Aetna
  
Edward Ellison, M.D.
Executive Medical Director/Chairman of the Board,
Southern CA Permanente Medical Group
 
    
Reed Tuckson, M.D.
Managing Director, Tuckson Health Connections LLC  
12:00 p.m.
Keynotes
 
"International Efforts for Implementing
Personalized Medicine"
 

 
Pierre Meulien, Ph.D.
President and Chief Executive Officer, Genome Canada
 
 
Professor Mark Caulfied, FMedSci
Director, William Harvey Research Institute, Barts and The London, Queen Mary's School of Medicine and Dentistry, Queen Mary University of London, UK
 
12:30 p.m.
Bag Lunch
Open Seating
 1:30 p.m.
Keynote
 
"Novel Solutions - Crowdsourcing: A New Approach for Innovation in Personalized Medicine"
Karim R. Lakhani, Ph.D., M.S.
Lumry Family Associate Professor of Business Administration, Harvard Business School;
Principal Investigator of the Harvard-NASA Tournament Lab at the Institute for Quantitative Social Science
 
Introducer:
Norman Selby
Executive Chairman, Real Endpoints LLC
 
2:00 p.m. 
Panel
 
"Big Data Meets Clinical Practice"
 
Although the price of DNA sequencing is decreasing, many are concerned that a similar decrease in the cost of analyzing and archiving genetic/genomic data is not forthcoming. This panel will explore the challenges of analyzing stroing, and sharing massive amounts of data and explore solutions that will support the practice of personalized medicine in the clinic.
Moderator:
Sandy Aronson
Executive Director of Information Technology, Parters HealthCare Center for Personalized Genetic Medicine
 
Colin Hill
CEO, President, Chairman, and Co-Founder
GNS Healthcare
 
Karim R. Lakhani, Ph.D., M.S.
Lumry Family Associate Professor of Business Administration, Harvard Business School;
Principal Investigator of the Harvard-NASA Tournament Lab at the Institute for Quantitative Social Science
 
Tom Miller
Founder, Grey BirdVentures
 
Charlie Schick, Ph.D.
Director of Big Data and Life Sciences in Healthcare, IBM
 3:00 p.m.
Closing Remarks
Raju Kucherlapati, Ph.D.

 
Paul C. Cabot Professor of Genetics, Professor of Medicine, Harvard Medical School